Having treated 5 cases of IgA Nephropathy in last 6 years and having live babies in pregnancy -I am writing this blog for public Awareness.
What is IgA Nephropathy in pregnancy?
- IgA nephropathy (also known as Berger’s disease) is the most common form of chronic glomerulonephritis affecting women of childbearing age.
- It is most often diagnosed between 16 and 35 years of age.
- IgA nephropathy can coexist with a number of other conditions such as systemic lupus erythematous,, hepatitis,
- Though the disease usually runs a slow course, with signs of renal damage visible in 10-20 years post-diagnosis, about 25% of adults with IgA nephropathy will develop endstage renal failure.
Effect of pregnancy on IgA nephropathy
- In women with; normal or near normal renal function before conception, pregnancy does not worsen the course of IgA nephropathy.
- Moderate to severe renal impairment ; pregnancy is not advisable
Pregnancy outcomes are largely determined by:
- Extent of pre-existent renal impairment
- Amount of proteinuria
- Significant tubule-interstitial damage found on renal biopsy.
TREATMENT
- Low-dose aspirin should be considered from about 12 weeks gestation onwards, continued till the end of pregnancy.
- Serial fetal growth scans from 26 weeks gestation at monthly intervals.
- Close monitoring of KFT & Fetal monitoring
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