ROLE OF VITAMIN D IN FERTILITY & INFERTILITY

In recent years a growing interest in vitamin D has been observed in Infertility Clinics & IVF Centres due to findings demonstrating a low vitamin D status in large section of the population. Vitamin D has been well-known for its function in maintaining calcium and phosphorus homeostasis and promoting bone mineralization. Vitamin D deficiency has been implicated in a host of chronic diseases, including diabetes, obesity, autoimmune disease, cardiovascular disease and cancer. More recently, poor vitamin D status has been implicated as a contributing factor to Poor Pregnancy Outcomes and Infertility in both men & women at Lifecare IVF Centre. In women, low vitamin D status is associated with Endometriosis and Polycystic Ovarian Syndrome. In men vitamin D deficiency leads to poor sperm parameters and function. Lifecare is one such IVF center in Delhi which is providing complete treatment and support to vitamin D deficient patients & creating awareness in public & expert forums about its bad effects.

VITAMIN D DEFICIENCY IN MALES

It is a myth that males do not suffer VIT-D deficiency. Air conditioners at office, cars and homes – have brought this menace in men too.

We have noted that male infertility due to day today stress & environmental factors is responsible for an all time low quality of semen, with concentrations well below healthy levels. At least 20% of young men have sperm concentration below what is expected and 40% have sperm concentrations inferior to what is considered optimal for fertility. In men, vitamin D status might be related to spermatogenesis, semen quality, and testiculopathies as well as male hypogonadism. The literature suggests that many adverse aspects of male aging are a consequence of decreased levels of testosterone, most likely due to the lack of vitamin D.

WHAT DOES VITAMIN D THERAPY DO IN WOMEN & MEN.

1) Improves Fertility

2) Strengthens Bones

3) Provides Immune Support

4) Avoids complication of Polycystic Ovarian Syndrome (PCOS) & endometriosis

5) Improves Semen Quality (motility and morphology)

6) Improves Sperm Function

VITAMIN D DEFICIENCY AFFECTS OUTCOME OF FERTILITY & PREGNANCY TOO !!

For the Mother

  • Infertility
  • Preeclampsia
  • Gestational diabetes
  • Increased rate of C-Section
  • Bacterial vaginosis

For the Baby

  • Small size (low birth weight)
  • Impaired Growth
  • Skeletal malformations, and sometimes brittle bones
  • Seizures
  • Hypocalcemia (low bone density)
  • Type-1 Diabetes

For Both

  • Bone loss
  • Hip fractures
  • Suppressed immune response
  • Impaired hormone formation

Vitamin D acts in the body through a precursor known as 7-dehydrocholesterol. Here comes the role of UV-B solar rays. These rays cause the precursor to convert into vitamin D3 which is then transported around the body by the vitamin D binding protein. According to the study, 80-90% of the vitamin D used by the body comes from sunlight induced production in the skin. That is why it is important to expose our bodies to sunlight on a daily basis. The more we are able to take in sun rays for safe periods of 10-20 minutes a day, the more vitamin D the body will produce naturally and the stronger our immune systems will be. The absence of naturally produced vitamin D can be substituted with vitamin D supplements. Humans must intake between 4000 and 5000 IU of vitamin D daily through supplementation in order to keep healthy levels in their bodies.

To conclude more exposure to sun light results in higher rates of human reproduction, and less sun light causes the opposite effect. Seasonal variation of vitamin D levels might influence several pathways including altered endometrial development and altered oocyte development our experience & findings do emphasize that vitamin D does affect female reproduction including success of IVF & infertility in both males& females. Lifecare IVF specializes & speared heading the awareness in infertility treatment in Delhi NCR.

Our Hospital is one of the best IVF center in Delhi NCR, Dr. Sharda Jain is IVF Specialist in Delhi. She has long experience IVF treatment.

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